Voltammetric and amperometric transduction for solvent polymeric membrane ion sensors

This paper describes basic response features of solvent polymeric membrane ion sensors with voltammetric and amperometric transduction. The model systems used here contain no ionophore for simplicity reasons. Reasonable simplifications of the theory are introduced that allow one to understand the response mechanism in view of a practical application of these sensors. It is shown that ion-sensing membranes preferentially contain no ion-exchanger properties in order to function optimally in a voltammetric mode. As with the systems studied by Kihara, both liquid-polymer interfaces of the membrane are preferably polarizable. Specifically, they contain the highly lipophilic electrolyte tetradodecylammonium tetrakis(4-chlorophenyl)borate (ETH 500) in the membrane to improve lifetime, increase the magnitude of the potential window, and prohibit exchange reactions with sample ions. An ohmic behavior that is associated with an assisted electrolyte-transfer process is observed only above a threshold potential which can be quantitatively predicted by theory. The threshold potential depends on the nature and activity of sample anions and cations in the sample and inner filling solution of the membrane electrode. Within the experimental conditions discussed in this paper, these sensors seem to measure sample ion activities, not concentrations, since the rate-limiting step is the diffusion of extracted ions away from the interface into the membrane bulk. Similarly, no effect of sample stirring on the measured current is observed. This contrasts to work done on liquid-liquid electrolyte-transfer reactions, where large diffusion coefficients in the organic phase often lead to substantial sample depletion effects. The detection of anions and cations with the same membrane is demonstrated in a cyclic voltammetric mode. Direct continuous detection of one type of anion is accomplished by pulsed amperometry to ensure a rapid, repetitive renewal of the membrane composition between measurements.