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Depressive symptomatology in coronary artery bypass graft surgery patients
P A Pirraglia1, J C Peterson, P Williams-Russo
1Brown University School of Medicine, Department of Medicine, Providence, RI, USA.
Insights
Depression is common in coronary artery bypass graft (CABG) patients. Psychosocial interventions may benefit those with low support, stressors, or longer ICU stays, as these factors correlate with depressive symptoms.
Area of Science:
- Cardiology
- Psychiatry
- Health Psychology
Background:
- Depression is frequently observed in patients undergoing coronary artery bypass graft (CABG) surgery.
- Understanding factors associated with depressive symptomatology is crucial for patient care.
Purpose of the Study:
- To examine the relationship between preoperative characteristics, life stressors, social support, and major outcomes with depressive symptomatology in CABG patients.
- To identify predictors of preoperative and postoperative depressive symptoms.
Main Methods:
- A cohort of 237 CABG patients was assessed for demographic and clinical data, depressive symptomatology (using the CES-D score), life stressors, and social support.
- Multivariate models were used to analyze associations with preoperative and postoperative CES-D scores.
- Follow-up was conducted at 6 months for 92% of participants.
Main Results:
- Significant depressive symptomatology was present in 43% preoperatively and 23% postoperatively.
- Preoperative depression was linked to low social support, recent life stressors, dyspnea, lack of available help, and lower education.
- Longer intensive care unit (ICU) stays and lack of available help predicted higher postoperative depressive symptoms.
Conclusions:
- A substantial proportion of CABG patients experience preoperative depression, which decreases postoperatively.
- Patients with specific preoperative risk factors or prolonged ICU stays may benefit from targeted psychosocial interventions.
- Depressive symptomatology did not correlate with major adverse cardiac or neurologic outcomes.
Abstract:
Depression is commonly reported in coronary artery bypass graft (CABG) surgery patients. This study assesses the relationship of preoperative characteristics, life stressors, social support, major cardiac and neurologic outcomes and other complications to depressive symptomatology. Demographic and clinical data, CES-D score and information on life stressors and social support were collected from 237 patients; 92% completed 6-month follow-up. CES-D score > or = 16 was defined as significant depressive symptomatology. Significant depressive symptomatology was found in 43% of patients preoperatively and 23% postoperatively. In multivariate models, low social support (p = 0.008), presence of at least one life stressor within a year of surgery (p = 0.006), moderate to severe dyspnea (p = 0.003), little to no available help (p = 0.05) and less education (p = 0.05) were associated with higher preoperative CES-D score, while longer intensive care unit (ICU) stay (p = 0.0001) and little or no available help (p = 0.0008) predicted higher postoperative CES-D scores when controlling for preoperative CES-D scores. Neither pre- nor postoperative depressive symptomatology was related to major outcomes or other complications. A high rate of significant depressive symptomatology exists in CABG patients preoperatively, and it decreases significantly postoperatively. Patients with the above preoperative characteristics as well as those who stay in the ICU postoperatively for more than 2 days might benefit from psychosocial interventions.
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