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Comparative study of rice-based oral rehydration salt solution versus glucose-based oral rehydration salt solution
1Department of Paediatric Medicine, Pt BD Sharma Postgraduate Institute of Medical Sciences, Rohtak.
Insights
Rice-based oral rehydration salt (ORS) solutions did not significantly improve stool output or weight gain in children with acute diarrhea compared to standard glucose-based ORS. Both ORS types were equally effective in rehydration and correcting biochemical imbalances.
Area of Science:
- Pediatrics
- Gastroenterology
- Public Health
Background:
- Acute dehydrating diarrhea remains a significant health challenge in children worldwide.
- Oral rehydration salt (ORS) solutions are crucial for managing dehydration.
- Exploring alternative ORS formulations, like rice-based solutions, is important for improving treatment efficacy.
Purpose of the Study:
- To compare the efficacy of rice-based ORS with standard glucose-based ORS in children with acute dehydrating diarrhea.
- To evaluate differences in stool output, weight gain, and rehydration time between the two ORS groups.
Main Methods:
- A comparative study involving 100 children with acute dehydrating diarrhea.
- Children were divided into two groups: Group A (n=50) received rice-based ORS, and Group B (n=50) received WHO-standard glucose-based ORS.
- Key parameters assessed included stool output, percentage weight gain, ORS consumption volume, and time to initial rehydration.
Main Results:
- No significant difference was observed in mean stool output between the rice-based ORS group and the glucose-based ORS group.
- Percentage weight gain was comparable between both groups.
- Both rice-based and glucose-based ORS solutions demonstrated similar effectiveness in terms of ORS consumption, rehydration time, and correction of biochemical abnormalities.
Conclusions:
- Rice-based ORS did not show a significant advantage over standard glucose-based ORS in managing acute dehydrating diarrhea in children.
- Both formulations were equally effective in rehydration and improving clinical outcomes.
- Further research may be needed to explore potential benefits or specific indications for rice-based ORS.
Abstract:
One hundred children with acute dehydrating diarrhoea were studied. They were divided into two groups: Group A (n = 50) were given rice-based oral rehydration salt (ORS) solution and group B (n = 50) were given glucose-based ORS solution (WHO). There was no significant decrease in mean stool output and percentage weight gain with rice-based ORS. Both the groups were comparable for volume of ORS solution consumed, time taken for initial rehydration, mean stool output and for correcting biochemical abnormalities.