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Rhinocerebral mucormycosis: report of two cases
1Ankara Numune Hospital, Department of Plastic and Reconstructive Surgery, Turkey.
Abstract:
Rhinocerebral mucormycosis is a rare opportunistic infection caused by fungi. It is commonly fatal and aggressive infection localised paranasal sinuses and orbit. We report two cases had necrotising infection on the left nasolabial region. Despite aggressive surgical debridement and medical treatment, the patients died 6 and 7 days after admission. Plastic Surgeons should be aware when they have a patient with rapidly developing soft tissue infection over the paranasal sinuses and periorbital region. Combined treatment is mandatory for these patients. It usually results in death, but powerful efforts may save the patient.
Insights
Rhinocerebral mucormycosis, a rare fungal infection, is a fatal condition affecting the sinuses and orbit. Prompt recognition and combined surgical and medical treatment are crucial for potentially saving patients with this aggressive necrotising infection.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Plastic Surgery
Background:
- Rhinocerebral mucormycosis is a rare, aggressive, and often fatal opportunistic fungal infection.
- It typically affects the paranasal sinuses and orbit, leading to severe necrotising disease.
Observation:
- Two cases of necrotising infection in the nasolabial region due to this condition are presented.
- Both patients experienced rapid disease progression despite aggressive surgical debridement and medical management.
Findings:
- Despite intensive treatment, both patients succumbed to the infection within a week of admission.
- The aggressive nature of the infection highlights the challenges in managing advanced cases.
Implications:
- Plastic surgeons must maintain a high index of suspicion for rapidly developing soft tissue infections in the paranasal and periorbital areas.
- Combined surgical and medical treatment is mandatory, though outcomes remain poor, emphasizing the need for early diagnosis and intervention.
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