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Keloids and hypertrophic scars.

R S English1, P D Shenefelt

  • 1Department of Dermatology, University of South Florida, College of Medicine, Tampa, Florida, USA.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|September 22, 1999
PubMed
Summary
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Keloids and hypertrophic scars are challenging skin growths that often recur. Effective management requires a multimodal approach, combining traditional and newer therapies, with long-term observation crucial for assessing treatment success.

Area of Science:

  • Dermatology
  • Wound Healing
  • Scar Management

Background:

  • Keloids and hypertrophic scars are benign fibrous growths following skin trauma.
  • These scar types present significant therapeutic challenges due to high recurrence rates.

Purpose of the Study:

  • To review current literature on keloids and hypertrophic scars.
  • To provide updated information for improved physician understanding and treatment.

Main Methods:

  • A comprehensive literature search was conducted using Medline.
  • Relevant publications on scar treatment modalities were analyzed.

Main Results:

  • Established treatments include surgery with intralesional steroids/radiotherapy, silicone sheeting, pressure, and cryotherapy.

Related Experiment Videos

  • Emerging effective treatments include pulsed dye laser, interferon alfa-2b, and cultured epithelial autografts.

    • Conclusions:

    • Frequent recurrence makes keloids and hypertrophic scars a therapeutic dilemma.
    • Understanding pathogenesis may lead to therapies preventing keloid growth.
    • Multimodality treatment is key, with at least 2 years of observation needed to confirm recurrence absence.