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Biochemical markers of bone turnover
1University of Sheffield, Division of Clinical Sciences (NGHT), Northern General Hospital, Sheffield, UK.
Current Opinion in Nephrology and Hypertension
|September 24, 1999
Summary
Newer biochemical markers of bone turnover show promise for monitoring osteoporosis treatment. Careful application is needed to minimize variability and ensure accurate assessment of subtle bone changes.
Area of Science:
- Biochemistry
- Orthopedics
- Endocrinology
Background:
- Biochemical markers specific to bone enable the study of subtle bone turnover changes.
- These markers have been assessed in conditions like Paget's disease and chronic renal failure.
Purpose of the Study:
- To review the application of biochemical markers of bone turnover in osteoporosis.
- To evaluate the utility of newer markers in clinical practice.
Main Methods:
- Literature review of studies on biochemical markers of bone turnover.
- Analysis of data concerning the use of these markers in osteoporosis.
Main Results:
- Growing interest in biochemical markers of bone turnover for clinical practice.
- Data support the use of newer bone turnover markers for monitoring osteoporosis treatment.
Conclusions:
- Biochemical markers are valuable tools for studying bone turnover in osteoporosis.
- Careful attention to minimizing variability is crucial for effective monitoring of osteoporosis treatment using these markers.