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Platelet indices during normal pregnancy and pre-eclampsia

S Howarth1, L R Marshall, A L Barr

  • 1Department of Haematology, King Edward Memorial Hospital for Women, Western Australia.

Platelet count and mean platelet volume (MPV) were estimated in 349 normal pregnancies at various gestational stages, and in 30 cases of pre-eclampsia. A probability plot was constructed from these data using discriminant analysis of MPV versus platelet count for the pre-eclamptic versus normal pregnancies. The sensitivity for pre-eclampsia was 90% (27/30) and the specificity was 83.3%. This plot may be of use in confirming risk of pre-eclampsia.

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