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Reversible pancreatitis, hepatitis, and peripheral polyneuropathy associated with parenteral gold therapy
H Ben-Ami1, S Pollack, P Nagachandran
1Department of Internal Medicine C, Rambam Medical Center, Haifa, Israel. mdhaim@tx.technion.ac.il
The Journal of Rheumatology
|September 24, 1999
Abstract:
A 63-year-old man with seronegative rheumatoid arthritis developed acute pancreatitis, severe hepatitis, and sensorimotor polyneuropathy after receiving 150 mg of intramuscular aurothioglucose (gold). Positive lymphocyte transformation test to gold indicated a cell mediated hypersensitivity to the drug, while multiple investigations ruled out other underlying causes for his illness. After cessation of gold therapy a complete recovery occurred.