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Related Experiment Videos

Tuberculous neuroretinitis.

S U Stechschulte1, R Y Kim, E T Cunningham

  • 1The Francis I. Proctor Foundation and The Department of Ophthalmology, University of California San Francisco, School of Medicine, 94143-0944, USA.

Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society
|September 24, 1999
PubMed
Summary
This summary is machine-generated.

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Tuberculosis can cause neuroretinitis, presenting as optic disc edema and macular star. Prompt treatment with antituberculosis medicine resolved ocular inflammation and retinal detachment.

Area of Science:

  • Ophthalmology
  • Infectious Diseases
  • Neurology

Background:

  • Tuberculosis is a significant global health concern.
  • Ocular manifestations of tuberculosis can be diverse and challenging to diagnose.
  • Neuroretinitis, inflammation of the optic nerve and retina, requires thorough etiological investigation.

Observation:

  • A 43-year-old woman with prior tuberculosis exposure presented with unilateral optic disc edema and a partial macular star (neuroretinitis).
  • Approximately one year later, she developed exudative retinal detachment associated with bilateral multifocal choroiditis.
  • Diagnostic workup revealed a strongly positive purified protein derivative (PPD) skin test.

Findings:

  • The patient's presentation of neuroretinitis, followed by exudative retinal detachment and multifocal choroiditis, was attributed to tuberculosis.

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  • Antituberculosis therapy led to rapid resolution of choroidal infiltrates and complete flattening of the exudative retinal detachment.

    • Implications:

    • Tuberculosis should be included in the differential diagnosis for patients presenting with neuroretinitis, especially those with relevant exposure history.
    • Early diagnosis and treatment of tuberculous ocular disease can prevent vision loss.
    • This case highlights the importance of considering systemic infections in unexplained inflammatory eye conditions.