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Related Experiment Videos

Dissociated vertical divergence: a righting reflex gone wrong.

M C Brodsky1

  • 1Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock, USA.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|September 25, 1999
PubMed
Summary
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Dissociated vertical divergence (DVD) is an ocular motor disorder. This study proposes DVD is a primitive dorsal light reflex, a righting response that can manifest in humans with early-onset strabismus.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Vision Science

Background:

  • Dissociated vertical divergence (DVD) is an ocular motor disorder.
  • DVD is characterized by the slow, upward drift of one eye during binocular fixation.

Purpose of the Study:

  • To propose a novel hypothesis for the pathophysiology of DVD.
  • To reframe DVD as a manifestation of the dorsal light reflex.

Main Methods:

  • Theoretical review of ocular motor control and visual reflexes.
  • Analysis of the proposed dorsal light reflex mechanism.
  • Examination of the role of visual input asymmetry in vertical divergence.

Main Results:

  • The dorsal light reflex is a primitive visuo-vestibular reflex.

Related Experiment Videos

  • This reflex functions to restore vertical orientation in animals by equalizing binocular visual input.
  • The reflex is normally suppressed in humans but can manifest as DVD.

    • Conclusions:

    • DVD may represent a re-emergence of the suppressed dorsal light reflex.
    • Early-onset strabismus can disrupt normal binocular development, leading to DVD.
    • This perspective offers a new framework for understanding and potentially treating DVD.