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Thrombus formation after transcatheter closure of atrial septal defect
K La Rosée1, H J Deutsch, P Schnabel
1Klinik III für Innere Medizin der Universität zu Köln, Germany.
The American Journal of Cardiology
|September 25, 1999
Insights
Transcatheter closure of atrial septal defects using the ASDOS device commonly resulted in thrombotic layers. These thrombi typically resolved within six months, showing no signs of embolization.
Area of Science:
- Cardiology
- Medical Devices
- Echocardiography
Background:
- Transcatheter closure is a common procedure for atrial septal defects.
- Post-procedural thrombosis can be a concern after device implantation.
Purpose of the Study:
- To investigate the occurrence and resolution of thrombotic layers after transcatheter closure of atrial septal defects (ASDs) using the ASDOS device.
- To assess the clinical significance of these thrombotic findings.
Main Methods:
- Transesophageal echocardiography was used to detect thrombotic layers and/or atrial thrombi.
- Patients undergoing ASD closure with the ASDOS device were monitored post-procedure.
Main Results:
- Thrombotic layers and/or atrial thrombi were a usual finding post-transcatheter ASD closure with the ASDOS device.
- The size of these thrombotic structures regularly decreased over a 6-month period.
- No clinical signs of embolization were observed during the follow-up period.
Conclusions:
- The formation of thrombotic layers after ASD closure with the ASDOS device is common but appears to be a transient phenomenon.
- The observed resolution of thrombi without embolic events suggests a favorable safety profile for this device in the medium term.
Abstract:
Thrombotic layers and/or atrial thrombi were detected by transesophageal echocardiography as a usual finding after transcatheter closure of atrial septal defects with the ASDOS device. The size of the thrombotic structures regularly decreased within 6 months without any clinical signs of embolization.