Related Experiment Video

Updated: Oct 19, 2026

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure
07:41

Echocardiographic Evaluation of Atrial Communications before Transcatheter Closure

Published on: February 8, 2022

Thrombus formation after transcatheter closure of atrial septal defect

K La Rosée1, H J Deutsch, P Schnabel

  • 1Klinik III für Innere Medizin der Universität zu Köln, Germany.

The American Journal of Cardiology
|September 25, 1999
PubMed

Insights

Transcatheter closure of atrial septal defects using the ASDOS device commonly resulted in thrombotic layers. These thrombi typically resolved within six months, showing no signs of embolization.

Area of Science:

  • Cardiology
  • Medical Devices
  • Echocardiography

Background:

  • Transcatheter closure is a common procedure for atrial septal defects.
  • Post-procedural thrombosis can be a concern after device implantation.

Purpose of the Study:

  • To investigate the occurrence and resolution of thrombotic layers after transcatheter closure of atrial septal defects (ASDs) using the ASDOS device.
  • To assess the clinical significance of these thrombotic findings.

Main Methods:

  • Transesophageal echocardiography was used to detect thrombotic layers and/or atrial thrombi.
  • Patients undergoing ASD closure with the ASDOS device were monitored post-procedure.

Main Results:

  • Thrombotic layers and/or atrial thrombi were a usual finding post-transcatheter ASD closure with the ASDOS device.
  • The size of these thrombotic structures regularly decreased over a 6-month period.
  • No clinical signs of embolization were observed during the follow-up period.

Conclusions:

  • The formation of thrombotic layers after ASD closure with the ASDOS device is common but appears to be a transient phenomenon.
  • The observed resolution of thrombi without embolic events suggests a favorable safety profile for this device in the medium term.

More Related Videos

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence10:52

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence

Published on: December 23, 2022

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation28:13

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

Published on: February 26, 2013

Related Concept Videos

Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Clot Retraction and Fibrinolysis01:16

Clot Retraction and Fibrinolysis

After a fibrin clot is formed, the next step is clot retraction, a vital process facilitated by platelet contractile proteins, such as actin and myosin. These proteins pull the fibrin strands closer together and condense the clot. This action reduces the size of the clot, creating a smaller, denser structure that effectively seals off the damaged vessel. Clot retraction consolidates the clot and helps with wound healing by bringing the edges of the damaged blood vessel closer together.
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...