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Plasma lipid concentrations during episodic occupational stress
B S McCann1, G A Benjamin, C W Wilkinson
1Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Harborview Medical Center, Seattle 98104-2499, USA.
Summary
Psychological stress from increased work load can elevate plasma triglycerides and apolipoprotein B, potentially impacting coronary artery disease risk. This study examined lawyers during high-stress tax deadlines.
Area of Science:
- Cardiology
- Endocrinology
- Occupational Health
Background:
- Previous research on stress and plasma lipids in non-laboratory settings yielded inconclusive results.
- Understanding the impact of psychological stress on cardiovascular health markers is crucial.
Purpose of the Study:
- To investigate the association between psychological stress (increased work load) and plasma lipid concentrations.
- To determine if stress influences health behaviors related to lipid levels.
Main Methods:
- 173 lawyers were studied during high work load (tax deadlines) and usual work load periods.
- Plasma lipids, apolipoproteins, cortisol, blood pressure, and heart rate were measured.
- Self-reported stress, work load, time pressure, dietary intake, and exercise were assessed.
Main Results:
- High work load correlated with increased self-reported stress and work load.
- Plasma apolipoprotein B and triglyceride levels significantly increased during high work load.
- No significant changes were observed in dietary intake or exercise habits.
Conclusions:
- Psychological stress, specifically high work load, is linked to potentially atherogenic changes in plasma lipids.
- Short-term stress effects on lipids are small, but long-term stress may contribute to coronary artery disease development.
- Triglycerides and apolipoprotein B are key lipid factors affected by work-related stress.