Jove
Visualize
Contact Us

Related Experiment Videos

Helicobacter pylori and chronic bronchitis.

M Caselli1, E Zaffoni, M Ruina

  • 1Postgraduate School of Gastroenterology and Research Centre on Asthma and COPD, University of Ferrara, Italy.

Scandinavian Journal of Gastroenterology
|September 28, 1999
PubMed
Summary

Helicobacter pylori infection appears to significantly increase the risk of developing chronic bronchitis. This pilot study found a higher prevalence of H. pylori in chronic bronchitis patients compared to controls.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Italian multicentre study on the management of pLeural infection and empyema: IMPLE study.

Respiratory research·2025
Same author

Reply to Correspondence: The Bronchodilator and Anti-Inflammatory Effect of Long-Acting Muscarinic Antagonists in Asthma: An EAACI Position Paper.

Allergy·2025
Same author

Raising the bar in respiratory care by EUFOREA: report of the European Union Parliament Symposium, April 2024.

Frontiers in allergy·2025
Same author

Auto-antibodies against carbonyl-modified vimentin in COPD: potential role as a biomarker.

Journal of inflammation (London, England)·2025
Same author

The Bronchodilator and Anti-Inflammatory Effect of Long-Acting Muscarinic Antagonists in Asthma: An EAACI Position Paper.

Allergy·2024
Same author

Author Correction: Intravenous N-acetylcysteine in respiratory disease with abnormal mucus secretion.

European review for medical and pharmacological sciences·2024
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Medical Microbiology
  • Pulmonology
  • Epidemiology

Background:

  • Chronic infections, including Helicobacter pylori (H. pylori), have been linked to coronary heart disease (CHD).
  • H. pylori has also been associated with extradigestive diseases.
  • Chronic bronchitis is a respiratory condition marked by persistent inflammation.

Purpose of the Study:

  • To investigate the prevalence of H. pylori infection in patients with chronic bronchitis.
  • To compare H. pylori prevalence in chronic bronchitis patients versus a matched control group.

Main Methods:

  • An enzyme-linked immunosorbent assay (ELISA) IgG test was used for H. pylori diagnosis.
  • The study included 60 consecutive patients with chronic bronchitis and 69 matched control subjects.

Related Experiment Videos

  • Subjects were matched for age and social status.

    • Main Results:

    • 81.6% of chronic bronchitis patients were H. pylori-positive, compared to 57.9% in the control group (P = 0.0079).
    • The odds ratio for H. pylori infection was 3.2 (simple analysis) and 3.399 (logistic regression).
    • H. pylori infection was found to significantly increase the risk of chronic bronchitis.

    Conclusions:

    • H. pylori infection is suggested to increase the risk of developing chronic bronchitis.
    • This finding expands the known extradigestive associations of H. pylori beyond CHD.
    • Further research should explore clinical outcomes after H. pylori eradication therapy in affected patients.