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Related Experiment Videos

Aortic calcification contributing to bone densitometry measurement.

J A Smith1, J A Vento, R P Spencer

  • 1Division of Endocrinology, Department of Medicine, University of Connecticut Health Center, Farmington, CT 06030-2804, USA.

Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry
|September 28, 1999
PubMed
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Aortic calcifications can significantly inflate lumbar bone density measurements, potentially leading to osteoporosis misdiagnosis. This finding is crucial for accurate bone mineral density assessment in elderly patients.

Area of Science:

  • Gerontology
  • Radiology
  • Endocrinology

Background:

  • Glucocorticoid therapy in asthma patients necessitates bone mineral density assessment for osteoporosis.
  • Elderly individuals are at higher risk for osteoporosis and aortic calcification.

Observation:

  • A 75-year-old male asthmatic on glucocorticoids presented with findings suggestive of osteoporosis.
  • Lumbar spine radiography revealed vertebral osteopenia, scoliosis, and a highly calcified abdominal aorta.
  • Dual-energy X-ray absorptiometry (DXA) showed low bone mass but an abnormal pattern due to aortic calcification.

Findings:

  • A calcified aorta contributed up to 33% of the measured lumbar bone density (L2-L4).
  • Lateral DXA measurements confirmed the aorta's density was comparable to the L2 vertebra.

Related Experiment Videos

  • This aortic contribution to bone density is higher than previously reported.

    • Implications:

    • Aortic calcifications can lead to significant overestimation of lumbar bone density.
    • Failure to recognize aortic calcification may result in misclassification of osteoporosis.
    • Accurate interpretation of DXA scans requires consideration of vascular calcifications.