Related Experiment Video
Updated: Jul 12, 2026

RiboTag Immunoprecipitation in the Germ Cells of the Male Mouse
Published on: March 4, 2020
Alternative processing of the human and mouse raly genes(1)
I Khrebtukova1, A Kuklin, R P Woychik
1Life Sciences Division, Oak Ridge National Laboratory, P.O. Box 2009, Oak Ridge, TN, USA.
Abstract:
A human homolog(RALY) of the mouse Raly gene was isolated and sequenced, and shown to encode a novel protein isoform containing a 16 amino acid in-frame insert in the variable region of the protein. Analysis of the corresponding region of the mouse Raly gene demonstrated that this novel protein isoform is also present in the mouse. Comparative analysis of RALY cDNA and EST sequences suggests the presence of additional alternatively processed RALY transcripts. As in the mouse, the human RALY gene is widely expressed as a 1.7-kb transcript.
More Related Videos
05:48Removal of an Internal Translational Start Site from mRNA While Retaining Expression of the Full-Length Protein
Published on: March 16, 2022
10:49Establishment, Maintenance, Differentiation, Genetic Manipulation, and Transplantation of Mouse and Human Lacrimal Gland Organoids
Published on: February 3, 2023
Related Concept Videos
In-vitro Mutagenesis
Alternative RNA Splicing
There are five types of alternative RNA splicing that vary in the ways the pre-mRNA segments are removed or retained in the mature mRNA. The first...
RNA Editing
Exon Recombination
Exon shuffling follows “splice frame rules.” Each exon has three reading...