Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Kidney transplantation improves baroreceptor sensitivity.

U Gerhardt1, M Riedasch, M Steinmetz

  • 1Department of Medicine D, University of Münster, Germany.

International Journal of Cardiology
|September 29, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A critical review of wire injury induced aortic valve stenosis in mice.

Journal of molecular and cellular cardiology·2022
Same author

[Resuscitation of children during the SARS-CoV-2 pandemic-a balance between self-protection and the factor of time].

Notfall & rettungsmedizin·2020
Same author

Author Correction: Nearly all the sky is covered by Lyman-α emission around high-redshift galaxies.

Nature·2018
Same author

Nearly all the sky is covered by Lyman-α emission around high-redshift galaxies.

Nature·2018
Same author

Impact of anticoagulation and vasoactive medication on regained radial artery patency after catheterization: a case-control study.

European journal of medical research·2018
Same author

Corrigendum: A large light-mass component of cosmic rays at 10<sup>17</sup>-10<sup>17.5</sup> electronvolts from radio observations.

Nature·2016

Kidney transplant and dialysis patients show reduced sympathetic nervous system activity. While hemodialysis patients have impaired baroreceptor sensitivity, kidney transplant recipients do not, suggesting it doesn't drive their cardiovascular disease risk.

Area of Science:

  • Cardiovascular Physiology
  • Nephrology
  • Neuroscience

Background:

  • Kidney transplant recipients and hemodialysis patients face elevated cardiovascular disease (CVD) risks.
  • Central neural blood pressure regulation is a potential contributing factor to CVD in these populations.

Purpose of the Study:

  • To investigate baroreceptor function and sympathetic nervous system (SNS) activity in kidney transplant recipients and hemodialysis patients.
  • To compare these parameters with age-matched healthy volunteers to understand CVD risk modulation.

Main Methods:

  • Utilized sequence analysis and Fast Fourier Transformation (FFT) to assess baroreceptor sensitivity and SNS activity.
  • Evaluated 20 kidney transplant recipients, 20 hemodialysis patients, and 20 healthy controls.

Related Experiment Videos

Main Results:

  • No significant differences in blood pressure were observed between the groups.
  • Hemodialysis patients exhibited reduced baroreceptor sensitivity compared to controls and transplant recipients.
  • Both kidney transplant and hemodialysis patients demonstrated decreased sympathetic nervous system activity compared to controls.

Conclusions:

  • Kidney transplant recipients and hemodialysis patients show reduced sympathetic nervous system activity.
  • Baroreceptor sensitivity is preserved in kidney transplant recipients, unlike in hemodialysis patients, suggesting it may not be a primary driver of CVD in transplant patients.