[Drug administration through a tube to patients with enteral nutrition. Centralization in in pharmacy service]

The administration of a drug through the nasogastric tube, in most cases requires a modification of the pharmaceutical form in order to achieve a good absorption and to avoid adverse effects. In this way, placing a tube in the duodenum or the jejunum requires administration of the drug in a manner that is dispersed, diluted and adequate in osmolarity. This study discusses the factors that must be taken into consideration in order to adapt the pharmaceutical base form for the nasoenteric administration of the drugs in order to decrease the number of complications derived from using this route, ensure the efficacy of the treatment, and to potentiate the nasoenteral-enterostomy route as opposed to the parenteral route. Keeping these factors in mind, the Pharmacy Department established a program for centralizing the preparation of extemporeal mixtures of medications in single dose syringes that are ready for nasoenteral use.