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Updated: Aug 11, 2026

Preparation, Purification, and Characterization of Lanthanide Complexes for Use as Contrast Agents for Magnetic Resonance Imaging
Published on: July 21, 2011
P760 and P775: MRI contrast agents characterized by new pharmacokinetic properties
1GUERBET, Department of Research, Roissy, France. portm@guerbet-group.com
Rationale And Objectives:
In this paper we discuss novel MR imaging blood pool agents characterized by new pharmacokinetic properties.
Methods:
The pharmacokinetics of the products were studied in a rabbit model. The potential of these new products was demonstrated in experimental MR imaging.
Results And Conclusion:
Three main classes of blood pool agents have been defined and characterized according to their pharmacokinetic properties: low diffusion agents, rapid clearance blood pool agents, slow clearance blood pool agents. Each kind of blood pool agent is expected to have different diagnostic applications.
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