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Dysphonia and delayed food allergy: a provocation/neutralization study with strobovideolaryngoscopy
1Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University, Rome, Georgia, USA.
Summary
Delayed food allergies may cause intermittent dysphonia, a voice disorder. Eliminating trigger foods resolved voice issues in a small study, suggesting a link between food sensitivities and vocal fold inflammation.
Area of Science:
- Otolaryngology
- Allergy Immunology
Background:
- Intermittent dysphonia often has an undiagnosed cause.
- Delayed food allergies are a potential, unexplored factor in voice disorders.
Purpose of the Study:
- To investigate the relationship between intermittent dysphonia and delayed food allergies.
- To identify the laryngeal changes associated with food-induced dysphonia.
Main Methods:
- Double-blind intradermal skin tests for food antigens in 10 subjects.
- Strobovideolaryngoscopy to assess vocal fold condition and voice quality.
- Perceptual, acoustic, and aerodynamic analyses of voice and laryngeal airflow.
Main Results:
- Dysphonia was linked to increased thick mucus and irregular vocal fold edema.
- Eliminating identified trigger foods resolved dysphonia in all participants.
- Vocal fold inflammation and mucus production were observed during allergic reactions.
Conclusions:
- Delayed food allergies may be a significant cause of intermittent dysphonia.
- Identifying and eliminating specific food triggers can effectively treat this voice condition.
- Further research with larger sample sizes is warranted to confirm these findings.