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Updated: Aug 7, 2026
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A Method for Ovarian Follicle Encapsulation and Culture in a Proteolytically Degradable 3 Dimensional System
Published on: March 15, 2011
[From theory to clinical practice: recombinant FSH in daily practice]
A Kably Ambe1, J Barrón Vallejo, A Góngora Rodríguez
1Unidad Reproducción Asistida, Centro de Fertilidad Humana en México.
Ginecologia Y Obstetricia De Mexico
|October 3, 1999
Summary
Recombinant follicle-stimulating hormone (FSH) effectively induces ovulation for both in vitro fertilization and embryo transfer (IVF-ET) and basic assisted reproductive techniques (ART). This study confirms its efficiency in achieving successful pregnancy outcomes in fertility treatments.
Area of Science:
- Reproductive Endocrinology
- Assisted Reproductive Technologies (ART)
Background:
- Ovulation induction is a critical component of assisted reproductive technologies.
- Recombinant follicle-stimulating hormone (FSH) offers a standardized and purified option for controlled ovarian stimulation.
Purpose of the Study:
- To evaluate the efficacy of ovulation induction using recombinant FSH in patients undergoing in vitro fertilization and embryo transfer (IVF-ET).
- To assess the effectiveness of recombinant FSH in basic assisted reproductive techniques (ART) protocols.
Main Methods:
- A total of 107 cycles were analyzed, divided into two groups: IVF-ET (n=12) and basic ART (n=95).
- Recombinant FSH was used for ovulation induction, with human chorionic gonadotropin (hCG) administered for final maturation.
- Oocyte retrieval occurred 34 hours post-hCG, followed by intrauterine insemination at 36 hours.
Main Results:
- The pregnancy rate per IVF-ET cycle was 25.0%.
- The pregnancy rate per basic ART cycle was 16.4%.
- Recombinant FSH demonstrated a favorable pregnancy rate in both treatment variations.
Conclusions:
- Ovulation induction with recombinant FSH is an effective and viable option for patients undergoing IVF-ET.
- Recombinant FSH is a suitable alternative for ovulation induction in basic ART protocols, yielding positive pregnancy rates.
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