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Bone changes in leprosy patients with disabilities/deformities (a clinico-radiological correlation)
H Choudhuri1, D M Thappa, R H Kumar
1Department of Dermatology and STD, JIPMER, Pondicherry.
Indian Journal of Leprosy
|October 3, 1999
Summary
Radiological examination revealed significant bone changes in 87.3% of leprosy patients, particularly linked to incomplete treatment and disease duration. Specific bone changes correlated with inadequate antileprosy treatment, while non-specific changes related to disease progression and disability.
Area of Science:
- Radiology
- Dermatology
- Infectious Diseases
Background:
- Leprosy, a chronic infectious disease, frequently leads to disabilities and deformities.
- Bone changes are a common but often under-evaluated complication of leprosy.
Purpose of the Study:
- To radiologically evaluate bone changes in leprosy patients with disabilities.
- To correlate these bone changes with clinical parameters such as treatment history and disease duration.
Main Methods:
- Radiological examination of 110 leprosy patients with disabilities/deformities.
- Correlation of observed bone changes with clinical data, including leprosy type, duration, treatment status, and disability index.
Main Results:
- A high prevalence of bone changes (87.3%) was observed, including specific (44.5%) and non-specific (75.5%) alterations.
- Specific bone changes were significantly associated with incomplete antileprosy treatment.
- Non-specific bone changes correlated with longer disease duration, incomplete treatment, and higher disability index.
Conclusions:
- Radiological bone changes are highly prevalent in leprosy patients with disabilities.
- Inadequate treatment is a significant risk factor for developing specific bone changes.
- Bone changes are closely linked to disease progression and patient disability.