Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

New developments in X-ray optics for macromolecular crystallography using laboratory X-ray sources.

U Arndt1, A Bloomer

  • 1Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK.

Current Opinion in Structural Biology
|October 6, 1999
PubMed
Summary

New devices improve X-ray beam conditioning for macromolecular crystal studies. These advancements enhance structural analysis of proteins and other biological molecules.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impact of the routine varicella vaccination programme on varicella epidemiology in Germany.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin·2010
Same author

[Overview of measles, mumps, rubella and varicella vaccination in adolescents and adults].

Deutsche medizinische Wochenschrift (1946)·2009
Same author

[Public health management in invasive meningococcal diseases].

Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany))·2004
Same author

Correction of iron-deficient erythropoiesis in the treatment of anemia of chronic disease with recombinant human erythropoietin.

Annals of hematology·2004
Same author

[Drug therapy of rheumatoid arthritis].

Der Orthopade·2003
Same author

Assessment of the genotoxicity of mine-dump material using the Tradescantia-stamen hair (Trad-SHM) and the Tradescantia-micronucleus (Trad-MCN) bioassays.

Mutation research·1999

Area of Science:

  • Crystallography
  • Structural Biology
  • Biophysics

Background:

  • Accurate structural determination of macromolecular crystals relies on precisely conditioned X-ray beams.
  • Existing methods for X-ray beam conditioning present limitations in performance and applicability.

Purpose of the Study:

  • To review and present recent advancements in devices for X-ray beam conditioning.
  • To highlight the impact of these devices on structural studies of proteins and macromolecular crystals.

Main Methods:

  • Literature review of recently developed X-ray beam conditioning devices.
  • Analysis of device performance characteristics for X-ray diffraction experiments.

Main Results:

  • Several novel devices have been developed for tailoring X-ray beam properties.

Related Experiment Videos

  • These devices offer improved control over beam intensity, focus, and spectral characteristics.

    • Conclusions:

    • Recent innovations in X-ray beam conditioning devices significantly benefit structural biology.
    • Optimized X-ray beams facilitate more detailed and accurate structural studies of macromolecules.