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Percutaneous autologous bone marrow grafting for simple bone cysts
1Osmangazi University, Medical Faculty, Department of Orthopaedics and Traumatology, Meselik, Eskisehir, Turkey.
Bulletin (Hospital for Joint Diseases (New York, N.Y.))
|October 6, 1999
Summary
Percutaneous autologous bone marrow grafting for simple bone cysts showed limited success. Factors like cyst size and multi-loculation significantly impact treatment outcomes, suggesting careful patient selection is crucial.
Area of Science:
- Orthopedics
- Regenerative Medicine
- Surgical Innovation
Background:
- Simple bone cysts (SBCs) are benign bone lesions often affecting long bones in children and adolescents.
- Current treatment options for SBCs have varying success rates and potential complications.
Purpose of the Study:
- To prospectively evaluate the efficacy of percutaneous autologous bone marrow grafting for treating simple bone cysts.
- To assess radiographic healing, complications, and clinical outcomes following this minimally invasive procedure.
Main Methods:
- Twelve patients with simple bone cysts underwent percutaneous aspiration of cyst fluid and injection of autologous bone marrow from the posterior iliac crest.
- Mean lesion volume was 51.2 cc, with a mean follow-up of 23 months.
Main Results:
- Complete radiographic healing was observed in only two patients (16.7%).
- Three cysts (25%) had residual defects requiring further intervention (curettage and bone grafting).
- Six cysts (50%) recurred, and one patient showed no healing.
Conclusions:
- Percutaneous autologous bone marrow grafting for simple bone cysts demonstrated a high recurrence rate and limited healing.
- Factors such as cyst size, multi-loculation, and complete cyst filling influence treatment success.
- This technique may be suitable for carefully selected patients, particularly those with smaller, unilobular cysts.