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Validation procedures in radiologic diagnostic models. Neural network and logistic regression
E Arana1, P Delicado, L Martí-Bonmatí
1Department of Radiology, Hospital Casa de Salud, Valencia, Spain.
Objective:
To compare the performance of two predictive radiologic models, logistic regression (LR) and neural network (NN), with five different resampling methods.
Methods:
One hundred sixty-seven patients with proven calvarial lesions as the only known disease were enrolled. Clinical and CT data were used for LR and NN models. Both models were developed with cross-validation, leave-one-out, and three different bootstrap algorithms. The final results of each model were compared with error rate and the area under receiver operating characteristic curves (Az).
Results:
The NN obtained statistically higher Az values than LR with cross-validation. The remaining resampling validation methods did not reveal statistically significant differences between LR and NN rules.
Conclusions:
The NN classifier performs better than the one based on LR. This advantage is well detected by three-fold cross-validation but remains unnoticed when leave-one-out or bootstrap algorithms are used.