Related Experiment Video

Updated: Jun 15, 2026

Isolation of Giant Lampbrush Chromosomes from Living Oocytes of Frogs and Salamanders
10:07

Isolation of Giant Lampbrush Chromosomes from Living Oocytes of Frogs and Salamanders

Published on: December 5, 2016

Karyotype study of Rana camerani and comparisons with the other 26-chromosome European brown frog species (Amphibia,

P Popov1, B Dimitrov

  • 1University of Plovdiv, Bulgaria.

Cytobios
|October 8, 1999
PubMed

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Karyotyping01:17

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Describing the number and physical features of chromosomes can reveal abnormalities that underlie genetic diseases. This description is facilitated by special staining techniques that produce a particular banding pattern on each chromosome. State-of-the-art techniques make this approach even more powerful, enabling the detection of individual genes that cause disease.A Simple Chromosome Staining Technique Provides Valuable Scientific InsightSome genetic diseases can be detected by looking at...
Lampbrush Chromosomes01:51

Lampbrush Chromosomes

In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
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Lampbrush Chromosomes01:51

Lampbrush Chromosomes

In 1882, Flemming observed lampbrush chromosomes (LBC) in salamander eggs. Later in 1892, Rückert observed LBCs in shark egg cells and coined the term "lampbrush chromosomes" because they looked like brushes used to clean kerosene lamps.
LBCs are made up of two pairs of conjugating homologous chromatids. Each chromatid consists of alternatively positioned regions of condensed-inactive chromatin and loosely placed-active side loops, which can be contracted and extended. The loops resemble the...