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Postpartum cerebellar herniation in von Hippel-Lindau syndrome
I S Othmane1, C Shields, A Singh
1Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.
Purpose:
To describe exacerbation during pregnancy of cerebellar hemangioblastoma in von Hippel-Lindau syndrome.
Method:
Case-report. A 21-year-old woman with von Hippel-Lindau syndrome was found on routine ocular examination to have severe papilledema 1 week after giving birth.
Results:
Immediate magnetic resonance imaging disclosed a large cerebellar cyst from hemangioblastoma causing cerebellar tonsillar herniation. Immediate neurosurgical intervention was life saving.
Conclusion:
Worsening of intracranial hemangioblastoma during pregnancy in cases of von Hippel-Lindau syndrome should be realized and periodic neurologic and ophthalmologic observation is warranted.