Orbital fibroblast interleukin-6 gene expression and immunomodulation

M A Burnstine1, S G Elner, R M Strieter

  • 1Department of Ophthalmology (W. K. Kellogg Eye Center), University of Michigan Medical School, Ann Arbor, USA.

Summary

Orbital fibroblasts (OFs) express interleukin-6 (IL-6) when exposed to inflammatory signals. Dexamethasone (DEX) inhibits this IL-6 production, while cyclosporin A (CSA) increases it, offering insights into orbital disease treatment.

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