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Related Experiment Videos

Thrombotic risk during pregnancy: a population study.

P Lindqvist1, B Dahlbäck, K Marŝál

  • 1Department of Obstetrics and Gynecology, and Coagulation Research, University of Lund, University Hospital, Sweden. pelle.lindqvist@obst.mas.lu.se

Obstetrics and Gynecology
|October 8, 1999
PubMed
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Pregnancy-related venous thromboembolic events occur in 13 of 10,000 deliveries. Key risk factors include cesarean delivery, advanced maternal age, smoking, and preeclampsia.

Area of Science:

  • Obstetrics and Gynecology
  • Thrombosis Research
  • Public Health

Background:

  • Venous thromboembolism (VTE) is a significant concern during pregnancy.
  • Understanding risk factors is crucial for prevention and management.

Purpose of the Study:

  • To determine the incidence of pregnancy-related VTE.
  • To investigate the association between VTE and maternal age, parity, smoking, preeclampsia, and cesarean delivery.

Main Methods:

  • A population-based cohort study in Sweden (1990-1993).
  • Compared 608 women with pregnancy-related VTE to 114,940 thrombosis-free pregnant women.
  • Utilized national health registries for data collection.

Main Results:

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  • The incidence of pregnancy-related VTE was 13 per 10,000 deliveries.
  • Cesarean delivery increased VTE risk fivefold.
  • Preeclampsia tripled postpartum VTE risk; smoking showed a dose-dependent risk increase.
  • Advanced maternal age was linked to increased cesarean rates, not a direct VTE risk factor.

    • Conclusions:

    • Pregnancy-related VTE incidence is 13 per 10,000 deliveries.
    • Identified cesarean delivery, smoking, preeclampsia, and age-related factors as significant risks.
    • Findings provide insights for targeted VTE prevention strategies in pregnant women.