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Related Experiment Videos

Lateralization of cortical function in swallowing: a functional MR imaging study.

K M Mosier1, W C Liu, J A Maldjian

  • 1Department of Oral Pathology Biology, New Jersey Dental School, University of Medicine and Dentistry of New Jersey, Newark 07103, USA.

AJNR. American Journal of Neuroradiology
|October 8, 1999
PubMed
Summary

Functional magnetic resonance imaging (fMRI) reveals specific motor cortex and subcortical brain areas activate during swallowing. This brain imaging technique shows hemispheric dominance for swallowing tasks, aiding dysphagia diagnosis.

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Area of Science:

  • Neuroscience
  • Medical Imaging

Background:

  • Functional brain localization is increasingly understood, but swallowing's neural basis remains unclear.
  • Existing neuroimaging methods have not been widely applied to the complex motor task of swallowing.

Purpose of the Study:

  • To investigate motor cortex activity during swallowing using functional magnetic resonance imaging (fMRI) in healthy adults.
  • To explore the cortical representation of swallowing and its potential diagnostic applications.

Main Methods:

  • Eight healthy adults underwent fMRI scans on a 1.5-T MR system using blood oxygen level-dependent (BOLD) contrast.
  • Subjects performed swallowing tasks and a control finger-tapping task.
  • Cortical and subcortical activation sites were identified, and a laterality index was calculated.

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Main Results:

  • Swallowing activated primary motor/sensory cortices, motor processing areas, and subcortical regions.
  • Activation showed hemispheric dominance, with left-hemisphere dominance observed more frequently.
  • Right-hemisphere dominance exhibited stronger lateralization compared to the left.

Conclusions:

  • Specific motor cortex, cortical, and subcortical areas are activated during swallowing, demonstrating hemispheric dominance.
  • fMRI is a valuable tool for studying the brain's control of swallowing.
  • fMRI may aid in diagnosing cerebral-origin dysphagia.