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Complex repetitive discharges: cause or effect of neurogenic muscle hypertrophy?
1Department of Neurological Sciences, Rush-Presbyterian-St. Luke's Medical Center, Rush University, 1725 West Harrison Street, Suite 1118, Chicago, Illinois 60612-3824, USA.
Muscle & Nerve
|October 8, 1999
Abstract:
We report a patient with adult-onset spinal muscular atrophy (SMA) of the scapulohumeral type with neurogenic muscle hypertrophy (NMH) in markedly weakened biceps muscles in association with continuous complex repetitive discharges (CRDs). This is an apparently unique case due to the bilaterality of the NMH associated with CRDs as well as the well-circumscribed symmetric upper extremity distribution of the hypertrophy. The possible mechanisms of NMH in association with spontaneous motor activity are discussed.