Simultaneous Optimization of Feeding Rate and Operation Parameters for Fed-Batch Fermentation Processes
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Published on: May 18, 2020
1Department of Chemical Engineering, National Chung Cheng University, Chia-Yi 621, Taiwan.
Abstract:
An efficient method is introduced for simultaneously determining optimal polices of feeding rate and operation parameters for a fermentation process. Such an optimization problem is converted into the finite dimensional optimization problem using the control parametrization technique. The hybrid differential evolution is introduced to solve the converted problem. The optimal production rate obtained by the simultaneous optimization approach could be significantly improved with comparison to a simplified optimization problem, which is considered the optimal feed control only, as observed from the simulation results.
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