Unusual premature ovarian failure with hypogonadotropic hyperprolactinemia and 46, XX, 13ph+

A 34-year-old woman with secondary amenorrhea is reported. She had a 30-day regular cycle menstruation from 12 to 24 years old. Her hormonal examination showed hypogonadotropic, secondary ovarian functional defect, and hyperprolactinemia. Her chromosomal arrangement was 46, XX, 13ph+ which is the elongation of 13p.