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Related Experiment Videos

Cystosarcoma phyllodes: the Western Australian experience.

D J Holthouse1, P A Smith, R Naunton-Morgan

  • 1Cancer Services Clinical Care Unit, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia. holthouse@hotmail.com

The Australian and New Zealand Journal of Surgery
|October 9, 1999
PubMed
Summary

Cystosarcoma phyllodes, a rare breast tumor, showed no recurrence in tumors under 2 cm. Breast-conserving surgery is effective for these phyllodes tumors.

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Area of Science:

  • Oncology
  • Breast Cancer Research
  • Surgical Pathology

Background:

  • Cystosarcoma phyllodes is a rare breast tumor with poorly understood clinical behavior.
  • Limited clinician awareness necessitates further research into phyllodes tumor management.

Purpose of the Study:

  • To investigate the clinical characteristics and outcomes of phyllodes tumors of the breast.
  • To evaluate recurrence patterns and surgical management of breast phyllodes tumors.

Main Methods:

  • Retrospective study of women diagnosed with phyllodes tumor of the breast.
  • Analysis of initial surgical treatment and follow-up data from Western Australian public hospitals (1983-1994).

Main Results:

  • Forty women diagnosed; 28 (70%) had follow-up.

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  • Median age at diagnosis was 46 years; 85.5% were Caucasian.
  • Four recurrences observed (1 malignant, 3 benign); no recurrence for tumors ≤ 2 cm. Mean recurrence time: 35.8 months.
  • Conclusions:

    • Breast-conserving surgery was the primary approach in 96.2% of initial operations.
    • Tumor size appears to be a significant factor in preventing recurrence.
    • Further understanding of phyllodes tumor behavior is crucial for optimal patient care.