Related Experiment Video
Updated: Aug 13, 2026
In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
Published on: May 1, 2020
Keloids and hypertrophic scars: results with intraoperative and serial postoperative corticosteroid injection therapy
N A Chowdri1, M Masarat, A Mattoo
1Department of Plastic and Reconstructive Surgery, Sher-i-Kashmir Institute of Medical Sciences, Soura, Srinagar (J&K), India.
Background:
The management of keloids and hypertrophic scars continues to be controversial. Experience of treating 58 such lesions, 58.62% of which were recurrent, is presented.
Methods:
Each lesion was subjected to surgical excision with intra-operative local injection of triamcinolone acetonide, followed by repeat injection of the same drug at weekly intervals for 2-5 weeks depending on the symptomatic relief, and then monthly injections for 4-6 months.
Results:
Complete symptomatic relief was achieved in all patients within 5 weeks of surgery. Objective response in terms of no recurrence was noted in 91.9% of patients with keloids, and 95.24% of patients with hypertrophic scars at a mean follow-up of 30.5 months. Local or systemic complications were insignificant.
Conclusion:
Because of promising results, further use and evaluation of this method of treatment is recommended for large, recurrent and complicated keloids and hypertrophic scars.
