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Published on: November 4, 2010
Left bronchial isomerism, normal atrial arrangement and bronchomalacia mimicking asthma: a new syndrome?
1Dept of Paediatric Respiratory Medicine, Royal Brompton Hospital, London, UK.
Abstract:
Three children who presented with steroid-resistant airflow obstruction are described. They all had bronchomalacia in the setting of a rare visceral arrangement, namely left bronchial isomerism with normal atrial arrangement. Imaging and, in two cases, a normal residual volume in the face of severe airflow obstruction were diagnostic pointers to a nonasthmatic cause of wheeze. Although the association of these abnormalities may be coincidental, together they may constitute a new clinical syndrome.
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