Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gender differences in postinfarction left ventricular remodeling.

S E Litwin1, S E Katz, C M Litwin

  • 1Cardiovascular Division, Salt Lake City Veterans Affairs Medical Center and University of Utah, Salt Lake City, Utah, USA. sheldon.litwin@hsc.utah.edu

Cardiology
|October 12, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of the Positive Muon Anomalous Magnetic Moment to 127 ppb.

Physical review letters·2025
Same author

A first vocal repertoire characterization of long-finned pilot whales (<i>Globicephala melas</i>) in the Mediterranean Sea: a machine learning approach.

Royal Society open science·2024
Same author

Measurement of the Positive Muon Anomalous Magnetic Moment to 0.20 ppm.

Physical review letters·2023
Same author

Measurement of the Positive Muon Anomalous Magnetic Moment to 0.46 ppm.

Physical review letters·2021
Same author

Paired EMI-HIMU hotspots in the South Atlantic-Starting plume heads trigger compositionally distinct secondary plumes?

Science advances·2020
Same author

Letters.

The Physician and sportsmedicine·2016

Gender influences heart remodeling after myocardial infarction (MI). Female rats showed less thickening of the non-infarcted left ventricle (LV) but similar LV enlargement and dysfunction compared to males, with better diastolic filling.

Area of Science:

  • Cardiovascular Research
  • Cardiac Physiology
  • Sex Differences in Medicine

Background:

  • Gender impacts cardiac adaptive responses to overload.
  • Left ventricular (LV) remodeling post-myocardial infarction (MI) and its gender-dependency are not fully understood.

Purpose of the Study:

  • To investigate if gender influences LV remodeling after MI.
  • To compare cardiac structural and functional changes in male and female rats post-MI.

Main Methods:

  • Transthoracic echocardiographic-Doppler examinations were performed in age-matched male and female rats.
  • Measurements were taken before, and 1 and 6 weeks after transmural MI or sham surgery.

Main Results:

  • Both male and female rats developed LV dilatation and systolic dysfunction after MI.

Related Experiment Videos

  • Male rats showed increased non-infarcted posterior wall thickness, unlike females.
  • Female rats exhibited less restricted LV diastolic filling compared to males.

    • Conclusions:

    • Female rats display distinct LV remodeling post-MI, with reduced non-infarcted wall thickening but comparable LV enlargement and systolic dysfunction.
    • Gender-related differences in LV remodeling may explain varied diastolic filling patterns and potentially influence clinical outcomes.