Next-generation adenoviral vectors: new and improved

Long-term, high-level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus.

Gene therapy·2016

Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2.

Cancer gene therapy·2013

TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses.

Journal of innate immunity·2010

CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies.

Gene therapy·2009

Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity.

Cancer gene therapy·2009

Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors.

Gene therapy·2008

An engineered helper plasmid generates differential E4orf6 and L4-22/33K gene expression increasing AAV vector production.

Gene therapy·2026

A gene therapy approach to prevent dilated intercellular space, a hallmark of gastroesophageal reflux disease.

Gene therapy·2026

Precision correction of the GJB2 c.235delC mutation by prime editing in vitro.

Gene therapy·2026

Bone- and muscle-targeted adeno-associated viral vectors enable tissue-selective vitamin D receptor knockdown in mice.

Gene therapy·2026

SACF and GILA for in vitro transformation assessment of CRISPR/Cas9-edited cell therapy candidates: a multi-site study.

Gene therapy·2026

rAAV production cost analysis: Indication-specific cost per dose and reduction strategies.

Gene therapy·2026

Cross-Linked Poly(Ethylene Carbonate/Ethylene Oxide) Electrolyte for Solid-State Li-Ion Batteries Exploiting Membrane-Electrode Assembly.

ACS polymers Au·2026

Field-enhanced graphene fiber arrays reveal serum metabolic alterations in pancreatic cancer.

Chemical science·2026

Electrical cardioversion for atrial fibrillation: nationwide trends in Denmark, 2010-2022.

Open heart·2026

Electric field-regulated extracellular polymeric substances enhance extracellular electron transfer at the biofilm-electrode interface.

Bioresource technology·2026

Ultra-high-frequency ECG quantifies residual electrical dyssynchrony during left bundle branch area pacing in patients with wide QRS: a paired within-patient study.

Journal of electrocardiology·2026

An integrated circularity and life cycle assessment of power electronic converters: key hotspots and improvement opportunities.

The Science of the total environment·2026

Related Experiment Videos

Next-generation adenoviral vectors: new and improved

Related Concept Videos

Long-term, high-level hepatic secretion of acid α-glucosidase for Pompe disease achieved in non-human primates using helper-dependent adenovirus.

Improved cytotoxic T-lymphocyte immune responses to a tumor antigen by vaccines co-expressing the SLAM-associated adaptor EAT-2.

TRIF, and TRIF-interacting TLRs differentially modulate several adenovirus vector-induced immune responses.

CR1/2 is an important suppressor of Adenovirus-induced innate immune responses and is required for induction of neutralizing antibodies.

Optimization of vaccine responses with an E1, E2b and E3-deleted Ad5 vector circumvents pre-existing anti-vector immunity.

Complex interactions with several arms of the complement system dictate innate and humoral immunity to adenoviral vectors.

An engineered helper plasmid generates differential E4orf6 and L4-22/33K gene expression increasing AAV vector production.

A gene therapy approach to prevent dilated intercellular space, a hallmark of gastroesophageal reflux disease.

Precision correction of the GJB2 c.235delC mutation by prime editing in vitro.

Bone- and muscle-targeted adeno-associated viral vectors enable tissue-selective vitamin D receptor knockdown in mice.

SACF and GILA for in vitro transformation assessment of CRISPR/Cas9-edited cell therapy candidates: a multi-site study.

rAAV production cost analysis: Indication-specific cost per dose and reduction strategies.

Cross-Linked Poly(Ethylene Carbonate/Ethylene Oxide) Electrolyte for Solid-State Li-Ion Batteries Exploiting Membrane-Electrode Assembly.

Field-enhanced graphene fiber arrays reveal serum metabolic alterations in pancreatic cancer.

Electrical cardioversion for atrial fibrillation: nationwide trends in Denmark, 2010-2022.

Electric field-regulated extracellular polymeric substances enhance extracellular electron transfer at the biofilm-electrode interface.

Ultra-high-frequency ECG quantifies residual electrical dyssynchrony during left bundle branch area pacing in patients with wide QRS: a paired within-patient study.

An integrated circularity and life cycle assessment of power electronic converters: key hotspots and improvement opportunities.

Related Experiment Videos

Next-generation adenoviral vectors: new and improved

Related Concept Videos

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