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Unusual breast lesions: radiologic-pathologic correlation.

J M Feder1, E S de Paredes, J P Hogge

  • 1Department of Radiology, Medical College of Virginia, Virginia Commonwealth University, Richmond 23298, USA.

Radiographics : a Review Publication of the Radiological Society of North America, Inc
|October 12, 1999
PubMed
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Unusual breast lesions, including systemic diseases and tumors, can mimic cancer on mammography and ultrasound. Radiologists must consider benign and systemic causes when evaluating suspicious breast findings.

Area of Science:

  • Radiology
  • Oncology
  • Pathology

Background:

  • Unusual breast lesions pose diagnostic challenges.
  • These include systemic diseases, benign tumors, and malignancies.
  • Mammographic and ultrasonographic findings can simulate breast cancer.

Purpose of the Study:

  • To review the imaging characteristics of unusual breast lesions.
  • To highlight differentiating features between benign and malignant breast masses.
  • To emphasize the importance of considering non-malignant differentials.

Main Methods:

  • Review of mammographic and ultrasonographic appearances of various breast lesions.
  • Correlation of imaging findings with histopathological diagnoses.
  • Discussion of differential diagnoses for malignant-appearing breast lesions.

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Main Results:

  • Systemic diseases like Wegener granulomatosis and diabetic fibrous mastopathy can mimic malignancy.
  • Benign tumors such as fibromatosis, granular cell tumors, hamartomas, and phyllodes tumors have characteristic imaging features.
  • Primary breast lymphoma and metastatic lesions present with specific mammographic and US findings.

Conclusions:

  • Radiologists must be aware of the diverse presentations of unusual breast lesions.
  • Considering benign and systemic conditions is crucial in the differential diagnosis.
  • Accurate interpretation aids in appropriate patient management and avoids unnecessary biopsies.