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Multilobated large B-cell lymphoma diagnosed cytologically. A case report
1Department of Pathology, University of Cincinnati Medical College, Ohio 45267-0529, USA.
Acta Cytologica
|October 13, 1999
Summary
Fine needle aspiration biopsy aids in diagnosing lymph node conditions. This case highlights its utility in identifying rare multilobated lymphomas, improving diagnostic accuracy.
Area of Science:
- Oncology
- Hematology
- Pathology
Background:
- Fine needle aspiration (FNA) biopsy is a valuable tool for lymph node diagnosis.
- It effectively classifies conditions or narrows differential diagnoses.
Observation:
- A 70-year-old male presented with an ulcerated tonsillar mass initially diagnosed as carcinoma.
- Systemic lymphadenopathy developed, and FNA biopsy of an axillary mass revealed a large cell lymphoma, multilobated type.
- Histologic and immunohistochemical studies confirmed a multilobated B-cell lymphoma.
Findings:
- Multilobated lymphomas are an uncommon variant of non-Hodgkin's lymphoma, predominantly B-cell type.
- Cytology and immunocytochemistry are crucial for diagnosing this rare lymphoma subtype.
- Accurate diagnosis significantly reduces the risk of misdiagnosis.
Implications:
- Early and accurate diagnosis of rare lymphoma subtypes is critical for patient management.
- FNA biopsy combined with immunocytochemistry enhances diagnostic precision for challenging cases.
- This approach can improve outcomes for patients with unusual lymphoid malignancies.