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Basic therapy for rheumatoid arthritis: nonsteroidal anti-inflammatory drugs
K F Daoud1, C G Jackson, H J Williams
1Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City 84132, USA.
Comprehensive Therapy
|October 16, 1999
Abstract:
Nonsteroidal anti-inflammatory drugs (NSAIDs) are often the initial treatment for rheumatoid arthritis. NSAID-induced inhibition of cyclooxygenase-2 (COX2) and cyclooxygenase-1 appears to correlate with clinical efficacy and toxicity, respectively. Newer NSAIDs with greater COX2 selectivity offer the promise of less toxic therapy.