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Related Experiment Videos

Multiple sclerosis, dental caries and fillings: a case-control study.

C W McGrother1, C Dugmore, M J Phillips

  • 1Department of Epidemiology and Public Health, University of Leicester.

British Dental Journal
|October 16, 1999
PubMed
Summary

Multiple sclerosis (MS) cases showed significantly more dental caries than controls. This suggests a link between MS and dental health, warranting further investigation into this association.

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Area of Science:

  • Neurology
  • Dental Medicine
  • Environmental Health

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease with multifactorial etiology.
  • Dental caries and exposure to heavy metals like mercury and lead are potential environmental factors influencing health outcomes.

Purpose of the Study:

  • To explore the association between multiple sclerosis (MS) and dental caries.
  • To investigate the role of amalgam fillings, and body mercury and lead levels in MS.

Main Methods:

  • A matched case-control study was conducted with 39 female MS patients and 62 controls.
  • Data collected via home interviews included the DMFT index (dental caries experience) and body levels of mercury and lead.

Main Results:

Related Experiment Videos

  • A statistically significant association was found between higher dental caries (DMFT index) and increased odds of MS.
  • No significant differences were observed in amalgam fillings or body mercury/lead levels between MS cases and controls.
  • A positive correlation existed between body mercury levels and the number of amalgam fillings in both groups.

Conclusions:

  • Evidence suggests a higher prevalence of dental caries in individuals with multiple sclerosis.
  • The findings support a potential geographical correlation between dental caries and MS.
  • Further research is recommended to elucidate the association between dental health and MS.