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Updated: Jul 11, 2026

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
Published on: November 3, 2010
The promise of comparative genomics in mammals
S J O'Brien1, M Menotti-Raymond, W J Murphy
1Laboratory of Genomic Diversity, National Cancer Institute, Frederick, MD 21702-1201, USA.
Abstract:
Dense genetic maps of human, mouse, and rat genomes that are based on coding genes and on microsatellite and single-nucleotide polymorphism markers have been complemented by precise gene homolog alignment with moderate-resolution maps of livestock, companion animals, and additional mammal species. Comparative genetic assessment expands the utility of these maps in gene discovery, in functional genomics, and in tracking the evolutionary forces that sculpted the genome organization of modern mammalian species.
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