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Updated: Aug 19, 2026

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
Published on: July 29, 2014
Development of a predictive statistical model for the analgesic activity of a family of imides
A D Andricopulo1, R A Yunes, V Cechinel Filho
1Departamento de Química, Universidade Federal de Santa Catarina (UFSC), Florianópolis, Brazil.
Abstract:
Quantitative structure-activity relationship (QSAR) studies were done with a family of cyclic imides. Promising efforts to create a QSAR model with substantial predictive power for the design of novel cyclic imides with improved analgesic activity are reported.
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