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[Intracellular signalization and inflammation: variations for an intracellular symphony. 1st movement]
1Institut national de la santé et de la recherche médicale, Inserm U430, hôpital Broussais, Paris, France.
Abstract:
Inflammatory response involves complex signalling pathways at cellular and molecular levels. During the cellular activation, intracellular substrates are subsequently phosphorylated for inducing transcription and synthesis of various inflammatory and/or anti-inflammatory mediators. This review focuses on the description of the main mechanisms involved in the activation signalling pathways that occur during inflammatory processes.