Related Experiment Video
Updated: Aug 9, 2026
15:06
Synthesis of an Intein-mediated Artificial Protein Hydrogel
Published on: January 27, 2014
Design, combinatorial chemical synthesis and in vitro characterization of novel urea based gelatinase inhibitors
1Pharmaceutical Science Division, School of Pharmacy, University of Wisconsin-Madison, 53706, USA.
Bioorganic & Medicinal Chemistry Letters
|October 16, 1999
Abstract:
A novel series of hydroxamate/urea-based inhibitors of gelatinases has been discovered via solid-phase combinatorial chemistry. SAR of P1', P2', and P3' has been exploited and structures different from traditional succinate-based MMP inhibitors have been found.
