[Characterization of myocardial tissue by ultrasound: backscatter]

One of the most important goals in Cardiology is to identify, noninvasively, the normal as well as pathological changes in structure and function of myocardial tissue in order to recognize their etiology and severity. Ultrasonic Tissue Characterization is an approach to define the physical state of the heart by the analysis of the pathological changes that modify cardiac tissue physical properties, therefore generating an ultrasonic signal alteration. Among the most practical types of analysis of this data is the acoustic parameters measurement, and measurements based on integrated backscatter have been utilized the most. Backscatter is the ultrasonic quantification reflected back to the transducer, therefore emanating from myocardial structures or "scatterers". This method has been used to study many patients with hypertrophy, cardiomyopathies, cardiac allograft rejection. But is the investigation of myocardial ischemia-viability one of the most clinically relevant applications because of the importance of selecting, non-invasively, and at a relatively low cost those patients with coronary artery disease in whom myocardial asynergy is noted by conventional echocardiography and/or angiography. The magnitude of alterations in backscatter measurements such as the cyclic variation of integrated backscatter are markers of myocardial viability and could better identify patients who stand to benefit the most revascularization procedures.