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Updated: Aug 14, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Prone and left lateral positioning reduce gastro-oesophageal reflux in preterm infants
A K Ewer1, M E James, J M Tobin
1Neonatal Unit, Birmingham Women's Hospital, Edgbaston, Birmingham B15 2TG. a.k.ewer@bham.ac.uk
Insights
Prone and left lateral body positions significantly reduce gastro-oesophageal reflux (GOR) severity in preterm infants. These positions decrease the number and duration of reflux episodes, aiding treatment.
Area of Science:
- Neonatal care
- Gastroenterology
- Pediatric medicine
Background:
- Gastro-oesophageal reflux (GOR) is a common clinical issue in preterm infants.
- Managing GOR is crucial for infant well-being and development.
Purpose of the Study:
- To investigate the impact of different body positions on clinically significant GOR in preterm infants.
- To determine if specific positions can mitigate reflux severity.
Main Methods:
- Prospective study involving 18 preterm infants with diagnosed GOR.
- Utilized 24-hour lower oesophageal pH monitoring.
- Infants were positioned prone, left lateral, and right lateral for 8-hour intervals, with random order assignment.
Main Results:
- Prone and left lateral positions significantly reduced the reflux index (RI) compared to the right lateral position (p<0.001).
- The number and duration of GOR episodes were substantially decreased in prone and left lateral positions (p<0.001).
- No significant difference was observed in the mean time spent in each position.
Conclusions:
- Prone and left lateral positioning are effective in reducing the severity of gastro-oesophageal reflux in preterm infants.
- These positions decrease both the frequency and longest duration of reflux episodes.
- Body positioning serves as a valuable complementary treatment for hospitalized preterm infants experiencing GOR.
Aim:
To examine the effect of body position on clinically significant gastro-oesophageal reflux (GOR) in preterm infants.
Methods:
Eighteen preterm infants with clinically significant GOR were studied prospectively using 24 hour lower oesophageal pH monitoring. Infants were nursed in three positions (prone, left, and right lateral) for 8 hours in each position, with the order randomly assigned. Data were analysed using analysis of covariance.
Results:
The median (range) reflux index (RI) for the group was 13.8% (5.8-40. 4). There was no significant difference in the mean time spent in each position. RI (mean % (SEM)) was significantly less in prone (6. 3 (1.7)) and left lateral positions (11.0 (2.2)), when compared with the right lateral position (29.4 (3.2)); p<0.001. The mean (SEM) longest episodes (mins) of GOR were reduced by prone and left positions (8.6 (2.2) and 10.0 (2.4), respectively) compared with the right position (26.0 (3.9)); p<0.001. The mean (SE) number of episodes was reduced by prone (15.4 (2.8)) and left (24.6 (3.5)) positions when compared with right (41.6 (4.6)) (p<0.001).
Conclusions:
Prone and left lateral positions significantly reduce the severity of GOR, by reducing the number of episodes and the duration of the longest episodes. Such positioning offers a useful adjunct to the treatment in hospital of preterm infants with gastro-oesophageal reflux.
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