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An introduction to the pathophysiology of osteoarthritis
1Joint Diseases Laboratory, Shriners Hospitals for Children and Division of Surgical Research, Department of Surgery, McGill University 1529 Cedar Avenue, Montreal, Quebec H3G 1A6 Canada. rpoole@shriners.mcgill.ca
Frontiers in Bioscience : a Journal and Virtual Library
|October 20, 1999
Abstract:
Osteoarthritis involves the degeneration of articular cartilage together with changes in subchondral bone and limited intra-articular inflammation. In this chapter these changes are reviewed at the tissue, cell and molecular levels to reveal the complexity of a process which involves multiple changes in joint structure and turnover.