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[Cognitive changes in normal aging: nosology and current status].

D Bartrés-Faz1, I Clemente, C Junqué

  • 1Departamento de Psiquiatría, Universitat de Barcelona, España. dbartres@psi.ub.es

Revista De Neurologia
|October 21, 1999
PubMed
Summary
This summary is machine-generated.

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This review compares diagnostic categories for adults with cognitive impairment but without dementia. Further research and consensus are needed to accurately identify age-related cognitive decline distinct from dementia.

Area of Science:

  • Gerontology
  • Neuroscience
  • Cognitive Psychology

Context:

  • Recent years have seen the emergence of diagnostic categories for adults exhibiting cognitive impairment relative to age-matched norms, yet without a dementia diagnosis.
  • Existing studies on these categories vary in prevalence and prognostic value, potentially due to differing diagnostic criteria and inclusion/exclusion protocols.
  • Genetic and neuroimaging findings increasingly support the validity of classifications aimed at characterizing age-related cognitive decline.

Purpose:

  • To review and compare major studies on diagnostic categories for adults with cognitive impairment but without dementia.
  • To determine if these categories describe similar or distinct aged populations.
  • To highlight the critical role of diagnostic criteria in distinguishing normal aging, mild cognitive impairment, and early dementia.

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Summary:

  • This work reviews and compares key studies on diagnostic categories for adults with cognitive impairment but without dementia.
  • Analysis suggests that differences in study outcomes may stem from variations in category selection and the application of inclusion/exclusion criteria.
  • Genetic and neuroimaging data bolster the validity of classifications for age-related cognitive decline.

Impact:

  • The findings underscore the importance of precise diagnostic criteria for accurately classifying cognitive function in aging populations.
  • Highlights the need for longitudinal studies and a consensus on existing categories to reliably differentiate individuals with lower cognitive function from those in early dementia stages.
  • Aims to improve the identification and characterization of cognitive changes associated with aging, distinct from neurodegenerative diseases.