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Operant responding for ethanol in rats with a long-term history of free-choice ethanol drinking
E Koros1, W Kostowski, P Bienkowski
1Department of Pharmacology and Physiology of the Nervous System, Institute of Psychiatry and Neurology, Warsaw, Poland.
Alcohol and Alcoholism (Oxford, Oxfordshire)
|October 21, 1999
Abstract:
Wistar rats were allowed to drink ethanol in a two-bottle (water vs 2-8% v/v ethanol) and then in a three-bottle choice paradigm (water vs 8% ethanol vs 16% ethanol, v/v). After 7 months of free access to alcohol, the subjects were trained to respond for 8% ethanol in an operant procedure. No relationship was found between prior alcohol drinking and lever pressing for ethanol.